The preparation of monoclonal antibody drugs by lymphocyte hybridoma technology or genetic engineering technology has become an important aspect in the field of biomedicine. With the great role of single cell cloning in clinical and diagnosis, monoclonal antibody technology has become an important part of the current biological research field. Let's introduce the process of discovering monoclonal antibodies by redbert (Beijing) Biotechnology Co., Ltd.
In the process of cell fusion, not only the two types of cells fuse, but also the two parent cells fuse with each other. Cells with two different parents are called heterokaryotes or heterokaryotes. The cells formed by the fusion of cells from the same parent are called homokaryons or homonuclear cells. Let redbert (Beijing) Biotechnology Co., Ltd. introduce the screening and cloning of fusion cells.
Due to the need for new biological resources, the preparation of lymphocyte hybridoma and monoclonal antibody, and the search for a new way of genetic material exchange between distant species, cell fusion technology has become one of the hotspots of life science research. Therefore, cell fusion method is the key to cell fusion. Next, redbert (Beijing) Biotechnology Co., Ltd. will introduce the common methods of cell fusion.
Hybridoma technology generally refers to B-lymphocyte hybridoma technology. That is, the immune spleen cells are hybridized with homologous animal myeloma cells by cell fusion technology, and the hybridized cells secreting predetermined specific antibodies are obtained by screening. Let's introduce hybridoma technology by redbert (Beijing) Biotechnology Co., Ltd.